Browsing by Discipline
Now showing items 21-40 of 133
-
Design, synthesis, and evaluation of novel lysophosphatidic acid receptor-targeting small molecules as therapeutic and diagnostic agents
(2023)Breast cancer has the highest incidence rate of all cancers among Canadian women and accounts for nearly 14% of all cancer-related deaths in Canada. This type of cancer is often detected using medical imaging modalities ... -
Development of an 18F radiolabeling method using solid phase chemistry
(2023)New radiotracers are constantly being developed to expand the clinical applications of positron emission tomography (PET). One of the challenges in the development of PET tracers is the incorporation of a positron emitting ... -
The development of an in-situ ATR-FTIR technique for the study of nanomaterials
(2009)The Fourier Transform Infrared Spectroscopy technique utilizes a short acquisition time and high sensitivity to function as a strong analytical tool in electrochemical studies. This work will focus on the development of ... -
Development of graphite based nanomaterials for green chemistry applications
(2017)Graphite is a valuable natural resource and useful carbon allotrope that has been explored for various applications. Graphene is a two-dimensional (2D) transparent material, which is the strongest, thinnest, and most ... -
The development of molecular probes for the in vitro and in vivo study of glucocerebrosidase
(2017)Parkinson’s Disease (PD) is one of the most common neurodegenerative diseases in the world. Despite its prevalence, the disease is difficult to diagnose early with the vast majority of individuals already having significant ... -
Development of multi-probe fluorescence-based assay for boNTA detection
(2015-08-05)Botulinum neurotoxins (BoNTs) cause the lethal disease botulism through the inhibition of acetyl choline secretion by the cleavage of crucial SNARE proteins. Determination of critical residues in the protein sequence of ... -
Development of small molecules targeting GPCRs (PAR2 and LPA1) for potential use in cancer diagnosis and therapy
(2025)Lung cancer continues to be the leading cause of cancer-related mortality for both men and women worldwide. Over the past two decades, advancements in prevention, screening, and treatment have contributed to reducing the ... -
Dielectric relaxation and infrared studies of hydrogen bonding
(1985)Dielectric relaxation and infrared study of a number of associating (H-bonding) compounds in glassy media, mainly polystyrene, have been carried out. The dielectric measurements by a General Radio 1621 Precision ... -
Dielectric relaxation studies of some diaryl molecules in polystyrene matrices
(1978)Dielectric relaxation studies of a number of diaryl molecules dispersed in atactic polystyrene and in some cases as solid discs have been carried out. Preparation of the polystyrene matrices and the solid disks, and the ... -
Dielectric studies of molecular and intramolecular motions in polystryrene matrices
(1977)Dielectric absorption studies of a variety of polar solutes containing rotatable groups and of some analogous rigid molecules dispersed in atactic polystyrene have been carried out. Preparation of the solutions as solid ... -
Dielectric studies of molecular motions in some solids
(1982)Dielectric absorption of a number of nonpolar, weakly polar and fairly polar molecules in the pure solid state are studied. Measurements of these solids using either a General Radio 1621 Precision Capacitance Measurement ... -
Dielectric studies of rigid and flexible molecules in various media
(1984)This thesis investigates mainly the molecular and intramolecular relaxation processes of some aromatic and aliphatic molecules containing rotatable polar groups and some analogous rigid molecules dispersed in (a) ... -
Dispersion and flocculation affinity of anionically charged kraft lignin
(2018)Softwood kraft lignin is a biodegradable, renewable, and environmentally friendly natural polymer. Although kraft lignin is widely produced in Canada, it is predominantly underutilized as fuel because it is only soluble ... -
The Effect of Pesticides on the Degradation of Oxobiodegradable Agricultural Mulch Films
(2015)Oxobiodegradable agriculture mulch films made from polyethylene (PE) are known to have many benefits for agriculture practice, including increased yields and resource efficiency, without the drawback of removing the ... -
Electrochemical oscillations during the anodic oxidation of sulfide
(2005)Sulfide is most often encountered as a waste product of the pulp and paper, petroleum, and mining industries. Organic decomposition is another major source of sulfide. During my M. Sc. program, I have studied electrochemical ... -
Enantioselective cross-coupling of monosubstituted ferrocenes in chiral ionic liquids
(2024)Planarly chiral ferrocenes have applications in pharmaceuticals, agrochemicals, and biomedical research for their use as ligands or catalysts in asymmetric synthesis. Previous methods of enantioselective synthesis of ... -
Expansion of the applicability of the Truce-Smiles rearrangement
(2022)The Truce-Smiles rearrangement is a synthetically useful and easily performed reaction which can be used to condense multiple steps of a synthesis. The nucleophilic aromatic substitution in this reaction produces a chiral ... -
Flocculation performance of lignin-acrylamide derivatives
(2019)Wastewater produced in different industries contains fine suspended particles that raise a number of environmental concerns due to their potential toxicity and physicochemical properties and make their removal from industrial ... -
Gallium nitride, indium nitride, and heterostructure development using the MEAglow growth system
(2014-12-11)This thesis presents an in depth study of semiconductor development using a new process termed Migration Enhanced Afterglow (MEAglow). The MEAglow growth reactor is housed in the Lakehead University Semiconductor Research ...
